产品服务
信号通路
说明书下载
货号: PH1246
货期: 一周
价格: 100μL/2200
靶点: GRB2
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Mouse
MW(Observed): 25kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of GRB2 and does not cross-react with related proteins.
基因名称 : grb2
蛋白名称 : Growth factor receptor-bound protein 2
别名 : GRB2;ASH;Growth factor receptor-bound protein 2;Adapter protein GRB2;Protein Ash;SH2/SH3 adapter GRB2
背景:
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],


微信客服