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货号: PD2322
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: K-Ras
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 22kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC: 100-300;WB 1:500-1:2000;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : K-Ras Polyclonal Antibody detects endogenous levels of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
基因名称 : KRAS
蛋白名称 : v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
别名 : GTPase KRas;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;[Cleaved into: GTPase KRas, N-terminally processed]
背景:
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],


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