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K-Ras Polyclonal Antibody

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说明书下载
货号: PD2322
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: K-Ras
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 22kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC: 100-300;WB 1:500-1:2000;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : K-Ras Polyclonal Antibody detects endogenous levels of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
基因名称 : KRAS
蛋白名称 : v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
别名 : GTPase KRas;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;[Cleaved into: GTPase KRas, N-terminally processed]

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endomembrane system . Cytoplasm, cytosol .; [Isoform 2B]: Cell membrane ; Lipid-anchor .

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