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TIP60 Monoclonal Antibody

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说明书下载
货号: PH1425
货期: 一周
价格: 100μL/2200
+


靶点: TIP60
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 59kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : TIP60 Monoclonal Antibody detects endogenous levels of TIP60 protein.
基因名称 : KAT5
蛋白名称 : Histone acetyltransferase KAT5
别名 : KAT5;HTATIP;TIP60;Histone acetyltransferase KAT5;60 kDa Tat-interactive protein;Tip60;Histone acetyltransferase HTATIP;HIV-1 Tat interactive protein;Lysine acetyltransferase 5;cPLA;2;-interacting protein

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],

细胞定位 : Nucleus . Chromosome . Cytoplasm . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle pole . Nucleus, nucleolus . Cytoplasm, perinuclear region . Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region and UV irradiation induces translocation into punctuate subnuclear structures named nuclear bodies (PubMed:11262386). Transiently localizes to kinetochores in early mitosis (PubMed:26829474). Localizes to spindle poles when chromosomes align during metaphase (PubMed:34608293). Localizes in the cytoplasm and nucleus of round spermatids (By similarity). .

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