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货号: PD5341
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: HLA-DPα1
应用: WB,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 29kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : HLA-DPα1 Polyclonal Antibody detects endogenous levels of HLA-DPα1 protein.
基因名称 : HLA-DPA1
蛋白名称 : HLA class II histocompatibility antigen DP alpha 1 chain
别名 : HLA-DPA1;HLA-DP1A;HLASB;HLA class II histocompatibility antigen;DP alpha 1 chain;DP;W3;DP;W4;HLA-SB alpha chain;MHC class II DP3-alpha;MHC class II DPA1
背景:
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008],


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