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货号: PH1818
货期: 一周
价格: 100μL/2200
靶点: BID
应用: WB,IHC,IF,Flow Cyt,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 22kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : BID Monoclonal Antibody detects endogenous levels of BID protein.
基因名称 : BID
蛋白名称 : BH3-interacting domain death agonist
别名 : BID;BH3-interacting domain death agonist;p22 BID;BID
背景:
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008],


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