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TFIIB Monoclonal Antibody

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说明书下载
货号: PH1326
货期: 一周
价格: 100μL/2200
+


靶点: TFIIB
应用: WB,IHC,IF
反应性 : Human,Mouse,Rat,Bovine,Chicken,Dog,Pig
宿主物种 : Mouse
MW(CalcμLated) : 35kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:100-1:500;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : TFIIB Monoclonal Antibody detects endogenous levels of TFIIB protein.
基因名称 : GTF2B
蛋白名称 : Transcription initiation factor IIB
别名 : GTF2B;TF2B;TFIIB;General transcription factor IIB;General transcription factor TFIIB;gtf2b;RNA polymerase II transcription factor IIB;S300 II;S300-II;TF IIB;TF2B;TF2B_HUMAN;TFIIB;Transcription initiation factor IIB.

数据库链接:

Organism

基因 ID

SwissProt

背景:

general transcription factor IIB(GTF2B) Homo sapiens This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008],

细胞定位 : Nucleus . Chromosome . Non-acetylated form colocalizes with DNA in the G0/1, S and G2 phases of the cell cycle, but not during mitosis (PubMed:24441171). Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase, anaphase, and telophase phases of the cell cycle (PubMed:24441171). .

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