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N-CoR Monoclonal Antibody

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说明书下载
货号: PH1531
货期: 一周
价格: 100μL/2200
+


靶点: NCOR1
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 270kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : N-CoR Monoclonal Antibody detects endogenous levels of N-CoR protein.
基因名称 : NCOR1
蛋白名称 : Nuclear receptor corepressor 1
别名 : NCOR1;KIAA1047;Nuclear receptor corepressor 1;N-CoR;N-CoR1

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010],

细胞定位 : Nucleus .

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