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详细信息
推荐稀释比 : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : PLZF Monoclonal Antibody detects endogenous levels of PLZF protein.
基因名称 : ZBTB16
蛋白名称 : Zinc finger and BTB domain-containing protein 16
别名 : ZBTB16;PLZF;ZNF145;Zinc finger and BTB domain-containing protein 16;Promyelocytic leukemia zinc finger protein;Zinc finger protein 145;Zinc finger protein PLZF
背景:
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008],


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