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推荐稀释比 ： ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0032
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD44 protein.
基因名称 ： CD44 LHR MDU2 MDU3 MIC4
蛋白名称 ： Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form]
别名 ： Blast 2 antibody;BLAST-2 antibody;Blast2 antibody;C type lectin domain family 4 member J antibody;C-type lectin domain family 4 antibody;C-type lectin domain family 4 member J antibody;C-type lectin domain family 4;member J antibody;CD 23 antibody;CD 23A antibody;CD23 antibody;CD23 antigen antibody;CD23A antibody;CLEC 4J antibody;CLEC4J antibody;Fc epsilon receptor II antibody;Fc epsilon RII antibody;Fc fragment of IgE antibody;Fc fragment of IgE low affinity II receptor for antibody;Fc fragment of IgE receptor II antibody;Fc fragment of IgE;low affinity II;receptor for;CD23;antibody;Fc of IgE antibody;Fc of IgE;low affinity II;receptor for;CD23;antibody;Fc receptor IgE low affinity II alpha polypeptide antibody;Fc receptor;IgE;low affinity II;alpha polypeptide;isoform CRA_a antibody;Fc-epsilon-RII antibody;FCE 2 antibody;FCE2 antibody;FCER 2 antibody;Fcer2 antibody;FCER2_HUMAN antibody;FCER2A antibody;FceRII antibody;IgE binding factor antibody;IgE receptor lymphocyte antibody;IgE-binding factor antibody;IGEBF antibody;Immunoglobulin E binding factor antibody;Immunoglobulin E receptor antibody;Immunoglobulin E receptor;low affinity II antibody;Immunoglobulin E-binding factor antibody;Immunoglobulin epsilon chain antibody;LEUKOCYTE ANTIGEN CD23 antibody;Low Affinity IgE Receptor antibody;Low affinity immunoglobulin epsilon Fc receptor antibody;Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody;Low affinity immunoglobulin epsilon Fc receptor soluble form antibody;Ly-42 antibody;Ly42 antibody;Lymphocyte antigen CD23 antibody;Lymphocyte IgE receptor antibody;MGC93219 antibody;CD23 nanobody;
背景：
The protein encoded byThis gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs).This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts forThis gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity ofThis protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
细胞定位 ： Cell membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli. Localizes to cholesterol-rich membrane-bound lipid raft domains. .
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