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推荐稀释比 ： ELISA 1:5000-100000
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0223
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD63 protein.
基因名称 ： CD63 MLA1 TSPAN30
蛋白名称 ： Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)
别名 ： Antigen identified by monoclonal antibody BB2 antibody;BB 2 antibody;BB2 antibody;CD 54 antibody;CD_antigen=CD54 antibody;CD54 antibody;Cell surface glycoprotein P3.58 antibody;Human rhinovirus receptor antibody;ICAM 1 antibody;ICAM-1 antibody;ICAM1 antibody;ICAM1_HUMAN antibody;intercellular adhesion molecule 1;CD54;antibody;intercellular adhesion molecule 1;CD54;human rhinovirus receptor antibody;Intercellular adhesion molecule 1 antibody;Major group rhinovirus receptor antibody;MALA 2 antibody;MALA2 antibody;MyD 10 antibody;MyD10 antibody;P3.58 antibody;Surface antigen of activated B cells antibody;Surface antigen of activated B cells;BB2 antibody;CD54 nanobody;
背景：
The protein encoded byThis gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency ofThis protein is associated with Hermansky-Pudlak syndrome. AlsoThis gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
细胞定位 ： Cell membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Endosome, multivesicular body . Melanosome . Secreted, extracellular exosome . Cell surface . Also found in Weibel-Palade bodies of endothelial cells (PubMed:10793155). Located in platelet dense granules (PubMed:7682577). Detected in a subset of pre-melanosomes. Detected on intralumenal vesicles (ILVs) within multivesicular bodies (PubMed:21962903). .
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