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GAPDH Monoclonal Antibody(2B8), AbFluor 350 Conjugated

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说明书下载
货号: PH1068
货期: 两周
价格: 100μL/2200
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靶点: GAPDH
应用: WB,IF,IHC
反应性 : Human,Rat,Mouse,Mk,Dg,Ch,Hamster,Rabbit,Pig,sheep,Insect,Yeast
宿主物种 : Mouse
同种型-Isotype : IgG1
偶联-Conjugate : AbFluor 350

隐藏域元素占位

详细信息

推荐稀释比 : Optimal working dilutions should be determined experimentally by the investigator;Suggested starting dilutions are as follows:IHC 1:200;IF 1:200.
组成 : Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
浓度 : 1mg/ml
克隆性 : Monoclonal
克隆号 : 2B8

抗原&靶点信息

特异性 : GAPDH Monoclonal Antibody(2B8) AbFluor™ 350 Conjugated specially designed for your Immunofluorescence analysis.
基因名称 : GAPDH
蛋白名称 : Glyceraldehyde-3-phosphate dehydrogenase
别名 : GAPDH

数据库链接:

Organism

基因 ID

SwissProt

背景:

glyceraldehyde-3-phosphate dehydrogenase(GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri

细胞定位 : Cytoplasm, cytosol . Nucleus . Cytoplasm, perinuclear region . Membrane . Cytoplasm, cytoskeleton . Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions (PubMed:12829261). .

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