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货号: PH0599
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: CDH4
应用: WB,IF,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Mouse
MW(CalcμLated) : 102kD
MW(Observed): 120kD
同种型-Isotype : IgG1,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein G
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Monoclonal
克隆号 : PT2127
抗原&靶点信息
特异性 : This antibody detects endogenous levels of R-Cadherin protein.
基因名称 : CDH4
蛋白名称 : Cadherin-4 (Retinal cadherin) (R-CAD) (R-cadherin)
别名 : Cadherin-4;Retinal cadherin;R-CAD;R-cadherin;
背景:
cadherin 4(CDH4) Homo sapiens This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],


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