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CDH3 Polyclonal Antibody

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说明书下载
货号: PD2009
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: P-cadherin
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 120kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:10000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of CDH3.
基因名称 : CDH3 CDHP
蛋白名称 : Cadherin-3 (Placental cadherin) (P-cadherin)
别名 : Cadherin-3;Placental cadherin;P-cadherin;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],

细胞定位 : Cell membrane; Single-pass type I membrane protein.

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