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货号: PD0290
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: AGRP
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 15kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000-2000;ELISA 1:5000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Human AGRP
基因名称 : AGRP AGRT ART
蛋白名称 : Agouti-related protein
别名 : AGRP;AGRT;ART;Agouti-related protein
背景:
disease:Defects in AGRP may be a cause of autosomal dominant obesity [MIM:601665].,domain:The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.,function:Plays a role in weight homeostasis. May play a role in the regulation of melanocortin receptors within the hypothalamus and adrenal gland, and therefore in the central control of feeding.,similarity:Contains 1 agouti domain.,tissue specificity:Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.,


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