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GABAA Rα1 Polyclonal Antibody

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说明书下载
货号: PD2467
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: GABAA Rα1
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 50kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : GABAA Rα1 Polyclonal Antibody detects endogenous levels of GABAA Rα1 protein.
基因名称 : GABRA1
蛋白名称 : Gamma-aminobutyric acid receptor subunit alpha-1
别名 : GABRA1;Gamma-aminobutyric acid receptor subunit alpha-1;GABA;A;receptor subunit alpha-1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane .

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