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GRIK2 (GluR6) Polyclonal Antibody

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说明书下载
货号: PG3283
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: GRIK2
应用: IHC,IF
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 103kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:100-200;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : GRIK2(GluR6) protein(A240) detects endogenous levels of GRIK2(GluR6)
基因名称 : GRIK2
蛋白名称 : Glutamate receptor, ionotropic kainate 2 (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)
别名 : Glutamate receptor, ionotropic kainate 2;Excitatory amino acid receptor 4;EAA4;Glutamate receptor 6;GluR-6;GluR6;

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

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