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货号: PD2101
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: Ob
应用: IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : The antibody detects endogenous Ob
基因名称 : LEP OB OBS
蛋白名称 : Leptin (Obese protein) (Obesity factor)
别名 : FLJ94114;LEP;LEP_HUMAN;LEPD;Leptin;murine obesity homolog;Leptin;obesity homolog, mouse;Leptin;Leptin Murine Obesity Homolog;Leptin Precursor Obesity Factor;OB;Obese Protein;Obese, mouse, homolog of;Obesity;Obesity factor;Obesity factor;Obesity homolog mouse;Obesity Murine Homolog Leptin;OBS;OTTHUMP00000212285.
背景:
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008],


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