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货号: PG8511
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类：
靶点: FAT1
应用： IHC,IF
反应性 ： Human
宿主物种 ： Rabbit
MW(Observed)： 504kD
同种型-Isotype ： IgG
隐藏域元素占位
详细信息
推荐稀释比 ： IHC 1:50-300;IF 1:50-200
组成 ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： FAT1 Polyclonal Antibody detects endogenous levels of protein.
基因名称 ： FAT1 CDHF7 FAT
蛋白名称 ： Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]
背景：
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008],
细胞定位 ： [Protocadherin Fat 1]: Cell membrane ; Single-pass type I membrane protein .; [Protocadherin Fat 1, nuclear form]: Nucleus .
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