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推荐稀释比 ： ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0288
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of GPR56 protein.
基因名称 ： ADGRG1 GPR56 TM7LN4 TM7XN1 UNQ540/PRO1083
蛋白名称 ： C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185)
别名 ： BLR1;MDR15;BLR 1 antibody;BLR1 antibody;Burkitt lymphoma receptor 1 antibody;Burkitt lymphoma receptor 1 GTP binding protein antibody;Burkitt lymphoma receptor 1;GTP binding protein;chemokine;C-X-C motif;receptor 5;antibody;C X C chemokine receptor type 5 antibody;C-X-C chemokine receptor type 5 antibody;CD 185 antibody;CD185 antibody;CD185 antigen antibody;Chemokine;C-X-C motif;receptor 5 antibody;Chemokine C X C motif receptor 5 antibody;Chemokine CXC motif receptor 5 antibody;Chemokine receptor 5 antibody;CXC chemokine receptor type 5 antibody;CXC R5 antibody;CXC-R5 antibody;CXCR 5 antibody;CXCR-5 antibody;Cxcr5 antibody;CXCR5_HUMAN antibody;MDR 15 antibody;MDR-15 antibody;MDR15 antibody;MGC117347 antibody;Monocyte derived receptor 15 antibody;Monocyte-derived receptor 15 antibody;
背景：
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations inThis gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
细胞定位 ： Cell membrane ; Multi-pass membrane protein .; [ADGRG1 N-terminal fragment]: Secreted .; [ADGRG1 C-terminal fragment]: Membrane raft . Interaction with its ligand COL3A1 leads to the release of ADGRG1 NT from the membrane and triggers the association of ADGRG1 CT with lipid rafts. .
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