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BMP-6 Polyclonal Antibody

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说明书下载
货号: PD2392
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: BMP-6
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 60kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : BMP-6 Polyclonal Antibody detects endogenous levels of BMP-6 protein.
基因名称 : BMP6
蛋白名称 : Bone morphogenetic protein 6
别名 : BMP6;VGR;Bone morphogenetic protein 6;BMP-6;VG-1-related protein;VG-1-R;VGR-1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016],

细胞定位 : Secreted .

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