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RASL1 Polyclonal Antibody

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说明书下载
货号: PG7558
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: RASL1
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 88kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : RASL1 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : RASAL1 RASAL
蛋白名称 : RasGAP-activating-like protein 1

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010],

细胞定位 : intracellular,cytosol,plasma membrane,intrinsic component of the cytoplasmic side of the plasma membrane,

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