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HGK Monoclonal Antibody

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说明书下载
货号: PH1634
货期: 一周
价格: 100μL/2200
+

所属分类:


靶点: HGK
应用: WB,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 142kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : HGK Monoclonal Antibody detects endogenous levels of HGK protein.
基因名称 : MAP4K4
蛋白名称 : Mitogen-activated protein kinase kinase kinase kinase 4
别名 : MAP4K4;HGK;KIAA0687;NIK;Mitogen-activated protein kinase kinase kinase kinase 4;HPK/GCK-like kinase HGK;MAPK/ERK kinase kinase kinase 4;MEK kinase kinase 4;MEKKK 4;Nck-interacting kinase

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

mitogen-activated protein kinase kinase kinase kinase 4(MAP4K4) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm .

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