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货号: PD2186
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: CIS
应用: IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : The antibody detects endogenous CIS
基因名称 : CISH G18
蛋白名称 : Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Protein G18) (Suppressor of cytokine signaling) (SOCS)
别名 : Cytokine-inducible SH2-containing protein;CIS;CIS-1;Protein G18;Suppressor of cytokine signaling;SOCS;
背景:
cytokine inducible SH2 containing protein(CISH) Homo sapiens The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],


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