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货号: PD2276
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: SPOP
应用: WB,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 42kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : SPOP Polyclonal Antibody detects endogenous levels of SPOP
基因名称 : SPOP
蛋白名称 : SPOP
别名 : Speckle-type POZ protein;HIB homolog 1;Roadkill homolog 1;
背景:
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],


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