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EST1 rabbit pAb

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说明书下载
货号: PG5587
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: EST1
应用: WB
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 60kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of EST1 at Human/Mouse
基因名称 : CES1 CES2 SES1
蛋白名称 : EST1
别名 : Liver carboxylesterase 1;Acyl-coenzyme A:cholesterol acyltransferase;ACAT;Brain carboxylesterase hBr1;Carboxylesterase 1;CE-1;hCE-1;Cocaine carboxylesterase;Egasyn;HMSE;Methylumbelliferyl-acetate deacetylase 1;Monocyte/macrophage serine esterase;Retinyl ester hydrolase;REH;Serine esterase 1;Triacylglycerol hydrolase;TGH;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],

细胞定位 : Endoplasmic reticulum lumen . Cytoplasm . Lipid droplet . Moves from cytoplasm to lipid droplets upon lipid loading. Associates with lipid droplets independently of triglycerides (TG) content of the droplets and hydrolyzes cholesteryl esters more efficiently from mixed droplets. .

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