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AK1C4 Polyclonal Antibody

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说明书下载
货号: PG8282
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: AK1C4
应用: WB,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 35kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : AK1C4 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : AKR1C4 CHDR
蛋白名称 : Aldo-keto reductase family 1 member C4 (3-alpha-HSD1) (3-alpha-hydroxysteroid dehydrogenase type I) (Chlordecone reductase) (CDR) (Dihydrodiol dehydrogenase 4) (DD-4) (DD4) (HAKRA)

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm, cytosol .

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