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货号: PH1244
货期: 一周
价格: 100μL/2200
靶点: HXK II
应用: WB
反应性 : Rat,Mouse,Monkey
宿主物种 : Mouse
MW(Observed): 102kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Hexokinase II and does not cross-react with related proteins.
基因名称 : hk2
别名 : DKFZp686M1669;Hexokinase 2;Hexokinase 2 muscle;Hexokinase type II;Hexokinase-2;HK 2;HK II;HK2;HKII;HxK 2;HxK2;HXK2_HUMAN;Muscle form hexokinase.
背景:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009],


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