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NLTP rabbit pAb

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说明书下载
货号: PG4650
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: NLTP
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 60kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of NLTP at Human/Mouse/Rat
基因名称 : SCP2
蛋白名称 : NLTP

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010],

细胞定位 : [Isoform SCP2]: Peroxisome . Cytoplasm . Mitochondrion . Endoplasmic reticulum . Mitochondrion .; [Isoform SCPx]: Peroxisome .

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