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Chitotriosidase Monoclonal Antibody

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说明书下载
货号: PH1754
货期: 一周
价格: 100μL/2200
+


靶点: Chitotriosidase
应用: WB,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 52kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : Chitotriosidase Monoclonal Antibody detects endogenous levels of Chitotriosidase protein.
基因名称 : CHIT1
蛋白名称 : Chitotriosidase-1
别名 : CHIT1;Chitotriosidase-1;Chitinase-1

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012],

细胞定位 : Secreted. Lysosome. A small proportion is lysosomal.

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