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货号: PH1754
货期: 一周
价格: 100μL/2200
所属分类:
靶点: Chitotriosidase
应用: WB,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 52kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : Chitotriosidase Monoclonal Antibody detects endogenous levels of Chitotriosidase protein.
基因名称 : CHIT1
蛋白名称 : Chitotriosidase-1
别名 : CHIT1;Chitotriosidase-1;Chitinase-1
背景:
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012],


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