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FMO3 Polyclonal Antibody

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说明书下载
货号: PD2557
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: FMO3
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 58kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : FMO3 Polyclonal Antibody detects endogenous levels of FMO3 protein.
基因名称 : FMO3
蛋白名称 : Dimethylaniline monooxygenase [N-oxide-forming] 3
别名 : FMO3;Dimethylaniline monooxygenase [N-oxide-forming] 3;Dimethylaniline oxidase 3;FMO II;FMO form 2;Hepatic flavin-containing monooxygenase 3;FMO 3;Trimethylamine monooxygenase

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

flavin containing monooxygenase 3(FMO3) Homo sapiens Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gen

细胞定位 : Microsome membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .

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