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货号: PD2741
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: DPYD
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 120kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : DPYD Polyclonal Antibody detects endogenous levels of DPYD protein.
基因名称 : DPYD
蛋白名称 : Dihydropyrimidine dehydrogenase [NADP(+)]
别名 : DPYD;Dihydropyrimidine dehydrogenase [NADP;+;];DHPDHase;DPD;Dihydrothymine dehydrogenase;Dihydrouracil dehydrogenase
背景:
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],


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