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CyPA Polyclonal Antibody

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说明书下载
货号: PD2768
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CyPA
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 18kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CyPA Polyclonal Antibody detects endogenous levels of CyPA protein.
基因名称 : PPIA
蛋白名称 : Peptidyl-prolyl cis-trans isomerase A
别名 : PPIA;CYPA;Peptidyl-prolyl cis-trans isomerase A;PPIase A;Cyclophilin A;Cyclosporin A-binding protein;Rotamase A

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm . Secreted . Nucleus . Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that includes Rho GTPase signaling, actin remodeling, and myosin II activation. .

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