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LXRα Polyclonal Antibody

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说明书下载
货号: PD2812
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: LXRα
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat,Golden hamster
宿主物种 : Rabbit
MW(Observed): 50kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : LXRα Polyclonal Antibody detects endogenous levels of LXRα protein.
基因名称 : NR1H3
蛋白名称 : Oxysterols receptor LXR-alpha
别名 : NR1H3;LXRA;Oxysterols receptor LXR-alpha;Liver X receptor alpha;Nuclear receptor subfamily 1 group H member 3

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

细胞定位 : Nucleus . Cytoplasm .

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