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V-ATPase B1 Polyclonal Antibody

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说明书下载
货号: PD3066
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: V-ATPase B1
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 60kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : V-ATPase B1 Polyclonal Antibody detects endogenous levels of V-ATPase B1 protein.
基因名称 : ATP6V1B1
蛋白名称 : V-type proton ATPase subunit B kidney isoform
别名 : ATP6V1B1;ATP6B1;VATB;VPP3;V-type proton ATPase subunit B;kidney isoform;V-ATPase subunit B 1;Endomembrane proton pump 58 kDa subunit;Vacuolar proton pump subunit B 1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found i

细胞定位 : Apical cell membrane . Basolateral cell membrane .

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