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推荐稀释比 ： WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： TAF II p135/p105 Polyclonal Antibody detects endogenous levels of TAF II p135/p105 protein.
基因名称 ： TAF4/TAF4B
蛋白名称 ： Transcription initiation factor TFIID subunit 4/Transcription initiation factor TFIID subunit 4B
别名 ： TAF4;TAF2C;TAF2C1;TAF4A;TAFII130;TAFII135;Transcription initiation factor TFIID subunit 4;RNA polymerase II TBP-associated factor subunit C;TBP-associated factor 4;Transcription initiation factor TFIID 130 kDa subunit;TAF;II;130;
数据库链接：
背景：
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and
细胞定位 ： Nucleus.
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