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Stat6 Polyclonal Antibody

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说明书下载
货号: PD3432
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Stat6
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Monkey
宿主物种 : Rabbit
MW(Observed): 94kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Stat6 Polyclonal Antibody detects endogenous levels of Stat6 protein.
基因名称 : STAT6
蛋白名称 : Signal transducer and activator of transcription 6
别名 : STAT6;Signal transducer and activator of transcription 6;IL-4 Stat

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],

细胞定位 : Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.

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