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SOCS-2 Polyclonal Antibody

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说明书下载
货号: PD3503
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: SOCS-2
应用: WB,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 22kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : SOCS-2 Polyclonal Antibody detects endogenous levels of SOCS-2 protein.
基因名称 : SOCS2
蛋白名称 : Suppressor of cytokine signaling 2
别名 : SOCS2;CIS2;SSI2;STATI2;Suppressor of cytokine signaling 2;SOCS-2;Cytokine-inducible SH2 protein 2;CIS-2;STAT-induced STAT inhibitor 2;SSI-2

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has

细胞定位 : cytoplasm,cytosol,

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