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详细信息
推荐稀释比 : WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : SMRTe Polyclonal Antibody detects endogenous levels of SMRTe protein.
基因名称 : NCOR2
蛋白名称 : Nuclear receptor corepressor 2
别名 : NCOR2;CTG26;Nuclear receptor corepressor 2;N-CoR2;CTG repeat protein 26;SMAP270;Silencing mediator of retinoic acid and thyroid hormone receptor;SMRT;T3 receptor-associating factor;TRAC;Thyroid-;retinoic-acid-receptor-associated
背景:
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011],


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