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货号: PD3546
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: Skp1 p19
应用： WB,IHC,IF,ELISA
反应性 ： Human,Mouse,Rat,Monkey
宿主物种 ： Rabbit
MW(Observed)： 19kD
同种型-Isotype ： IgG
隐藏域元素占位
详细信息
推荐稀释比 ： WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： Skp1 p19 Polyclonal Antibody detects endogenous levels of Skp1 p19 protein.
基因名称 ： SKP1
蛋白名称 ： S-phase kinase-associated protein 1
别名 ： SKP1;EMC19;OCP2;SKP1A;TCEB1L;S-phase kinase-associated protein 1;Cyclin-A/CDK2-associated protein p19;Organ of Corti protein 2;OCP-2;Organ of Corti protein II;OCP-II;RNA polymerase II elongation factor-like protein;SIII;Transcr;p19A;p19skp1;Transcription elongation factor B;
背景：
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008],
细胞定位 ： nucleus,nucleoplasm,cytoplasm,centrosome,cytosol,SCF ubiquitin ligase complex,Cul7-RING ubiquitin ligase complex,PcG protein complex,extracellular exosome,
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