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Sec16A Polyclonal Antibody

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说明书下载
货号: PD3623
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: Sec16A
应用: IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Sec16A Polyclonal Antibody detects endogenous levels of Sec16A protein.
基因名称 : SEC16A
蛋白名称 : Protein transport protein Sec16A
别名 : SEC16A;KIAA0310;SEC16;SEC16L;Protein transport protein Sec16A;SEC16 homolog A

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013],

细胞定位 : Endoplasmic reticulum membrane ; Peripheral membrane protein . Golgi apparatus membrane ; Peripheral membrane protein . Cytoplasm, perinuclear region . Cytoplasm, cytosol . Microsome membrane . SAR1A activity is required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation (PubMed:17192411). Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). MIA3 and LRRK2 are required for its proper localization to ERES (PubMed:25201882, PubMed:28442536, PubMed:19638414, PubMed:17428803, PubMed:22355596). Recruited to microsomal membrane in SAR1-dependent manner (PubMed:17428803). .

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