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RO60 Polyclonal Antibody

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说明书下载
货号: PD3684
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: RO60
应用: WB,IHC
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 70kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : RO60 Polyclonal Antibody detects endogenous levels of RO60 protein.
基因名称 : TROVE2
蛋白名称 : 60 kDa SS-A/Ro ribonucleoprotein
别名 : TROVE2;RO60;SSA2;60 kDa SS-A/Ro ribonucleoprotein;60 kDa Ro protein;60 kDa ribonucleoprotein Ro;RoRNP;Ro 60 kDa autoantigen;Sjoegren syndrome antigen A2;Sjoegren syndrome type A antigen;SS-A;TROVE domain family member 2

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.,function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Ro 60 kDa family.,similarity:Contains 1 TROVE domain.,subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.,

细胞定位 : Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .

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