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RGS10 Polyclonal Antibody

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说明书下载
货号: PD3769
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: RGS10
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 20kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : RGS10 Polyclonal Antibody detects endogenous levels of RGS10 protein.
基因名称 : RGS10
蛋白名称 : Regulator of G-protein signaling 10
别名 : RGS10;Regulator of G-protein signaling 10;RGS10

数据库链接:

Organism

基因 ID

SwissProt

背景:

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : [Isoform 1]: Cytoplasm, cytosol . Nucleus . Forskolin treatment promotes phosphorylation and translocation to the nucleus. .; Nucleus .

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