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Raftlin Polyclonal Antibody

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说明书下载
货号: PD3840
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: Raftlin
应用: WB,IHC
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 65kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Raftlin Polyclonal Antibody detects endogenous levels of Raftlin protein.
基因名称 : RFTN1
蛋白名称 : Raftlin
别名 : RFTN1;KIAA0084;MIG2;Raftlin;Cell migration-inducing gene 2 protein;Raft-linking protein

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

function:May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling.,similarity:Belongs to the raftlin family.,subcellular location:Associates with lipid rafts.,tissue specificity:Specifically expressed by B-cells (at protein level).,

细胞定位 : Cell membrane ; Lipid-anchor . Cytoplasm . Membrane raft . Endosome . Early endosome . Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3 (PubMed:21266579). Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195). .

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