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Rab11-FIP2 Polyclonal Antibody

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说明书下载
货号: PD3870
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Rab11-FIP2
应用: WB,ELISA,IHC
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 58kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.
基因名称 : RAB11FIP2
蛋白名称 : Rab11 family-interacting protein 2
别名 : RAB11FIP2;KIAA0941;Rab11 family-interacting protein 2;Rab11-FIP2;NRip11

数据库链接:

Organism

基因 ID

SwissProt

背景:

function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding.,

细胞定位 : Cell projection, phagocytic cup . Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.

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