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货号: PD4205
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: p52 S6 kinase
应用: WB,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 117kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : p52 S6 kinase Polyclonal Antibody detects endogenous levels of p52 S6 kinase protein.
基因名称 : RPS6KC1
蛋白名称 : Ribosomal protein S6 kinase delta-1
别名 : RPS6KC1;RPK118;Ribosomal protein S6 kinase delta-1;S6K-delta-1;52 kDa ribosomal protein S6 kinase;Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein;SPHK1-binding protein
背景:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,caution:Instead of Lys-820, Arg-820 is found at the binding site.,domain:The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site.,function:May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 MIT domain.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 2 protein kinase domains.,subcellular location:Also found in some small dot-like or ring-shaped early endosome structures.,subunit:Interacts with SPHK1 and phosphatidylinositol 3-phosphate.,tissue specificity:Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.,


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