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NPY Polyclonal Antibody

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说明书下载
货号: PD4520
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: NPY
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 11kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:100-500;WB 1:500-2000;ELISA 1:5000-20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : NPY Polyclonal Antibody detects endogenous levels of NPY protein.
基因名称 : NPY
蛋白名称 : Pro-neuropeptide Y
别名 : NPY;Pro-neuropeptide Y

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014],

细胞定位 : Secreted. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle .

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