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货号: PD4636
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: NEDL2
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 140-150kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : NEDL2 Polyclonal Antibody detects endogenous levels of NEDL2 protein.
基因名称 : HECW2
蛋白名称 : E3 ubiquitin-protein ligase HECW2
别名 : HECW2;KIAA1301;NEDL2;E3 ubiquitin-protein ligase HECW2;HECT;C2 and WW domain-containing protein 2;NEDD4-like E3 ubiquitin-protein ligase 2
背景:
function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with TP73.,tissue specificity:Predominantly expressed in adult brain, lung and heart.,


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