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NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody

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说明书下载
货号: PD4678
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: NBPF1/9/10/12/14/15/16/20
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 36kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody detects endogenous levels of NBPF1/9/10/12/14/15/16/20 protein.
基因名称 : NBPF12
蛋白名称 : Neuroblastoma breakpoint family member 12
别名 : NBPF12;COAS1;KIAA1245;Neuroblastoma breakpoint family member 12;Chromosome 1 amplified sequence 1;NBPF10;Neuroblastoma breakpoint family member 10;NBPF16;Neuroblastoma breakpoint family member 16;NBPF1;KIAA1693;Neuroblastoma brea
背景:

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This

细胞定位 : Cytoplasm .

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