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MLK1/2 Polyclonal Antibody

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说明书下载
货号: PD4851
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: MLK1/2
应用: IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 100-120kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : MLK1/2 Polyclonal Antibody detects endogenous levels of MLK1/2 protein.
基因名称 : MAP3K9/MAP3K10
蛋白名称 : Mitogen-activated protein kinase kinase kinase 9/10
别名 : MAP3K9;MLK1;PRKE1;Mitogen-activated protein kinase kinase kinase 9;Mixed lineage kinase 1;MAP3K10;MLK2;MST;Mitogen-activated protein kinase kinase kinase 10;Mixed lineage kinase 2;Protein kinase MST

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH3 domain.,subunit:Homodimer.,tissue specificity:Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.,

细胞定位 : intracellular,integral component of membrane,

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