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MLH1 Polyclonal Antibody

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说明书下载
货号: PD4855
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: MLH1
应用: WB,IHC
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 85kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : MLH1 Polyclonal Antibody detects endogenous levels of MLH1 protein.
基因名称 : MLH1
蛋白名称 : DNA mismatch repair protein Mlh1
别名 : MLH1;COCA2;DNA mismatch repair protein Mlh1;MutL protein homolog 1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],

细胞定位 : Nucleus . Chromosome . Recruited to chromatin in a MCM9-dependent manner. .

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